Welcome to the PhD Medical Biochemistry

The aim of PhD program in Biochemistry is to raise human power who is competitive, talented, reliable, self-contained and scientificly honest advanced knowledge, aware of recent findings in biochemistry and can establish and evaluate the structure-function relationship at molecular, cellular, tissue and system level who should be able to plan and perform an original research by himself/herself and should be able to present his/her findings to the universal scientific community.
Biochemical bases of genesis, diagnosis and treatment of cancer. To explain the molecular and cellular mechanisms that lead to generation and progression of cancer and propose methods how these may direct cancer diagnosis and treatment, to select and analyse articles dealing with these topics. Genesis of cancer, mechanisms involved in cell survival, senescence and death, genetic alterations that lead to cancer development and progression, molecules which are selected as targets in diagnosis and treatment of cancer, methods used in diagnosis, novel approaches in cancer treatment, effects of cancer drugs and drug resistance mechanisms.
The course covers the mechanisms of biomolecular reactions as reflected in kinetic patterns. The main approach is to present a series of illustrative examples, from simple chemical interconversions to enzymatic systems, pointing out the basic experimental approaches in kinetic investigation and the link between reaction mechanism and kinetic behavior. Lecture hours are dedicated mainly to the sampling of different reaction types. Hand-out sheets with quantitative and data interpretation type problems serve as homework. Part of the lecture program is allotted to class discussion of such hand-outs.