Welcome to the PhD. Pharmaceutical Technology

Targeting, targeting mechanisms, advantages – disadvantages and basic concepts in drug targeting will be studied. Discussion of basic concepts and information related to bioavailability and bioequivalance, bioavailability comparisons, statistical methods and criteria for for bioequivalance . Relation of pharmaceutical and therapeutic equivalence with dissolution rate and bioavailability.
Basic consepts on solid dosage forms and their production techniques, general characteristics of powders, determination of dynamic properties of powders, granulation methods, tablet production technolgy, coating technology, coated tablets, hard gelatin capsules, and their formulations, quality control tests will be studied. Formulation and optimization study of the solid dosage forms for parametric investigation of production methods.
Study of basic concepts about quality control and validation by discussion. Quality assurance, security,efficiency, validation types (retrospective, prospective), validation in different dosage forms, quality control,quality assurance and storage conditions are other topics of the course.
Basic concepts on micrometry, importance of particle size and distrubition in pharmaceutical technology. Study of basic principals of Trandermal and Transmucozal Drug Carrier Systems, their passing barriers penetration methods formulations function of exipients finish product.
Study of basic principals of Trandermal and Transmucozal Drug Carrier Systems, their passing barriers penetration methods formulations function of exipients finish product. Peptide and protein drug delivery systems and related concepts, new approaches to delivery of peptide and protein drugs into the body, giving information about the work of the formulation in order to increase the absorption and stability. Non-linear pharmacokinetics basic concepts, non-linear drugs and dose-response relation will be studied. Study of basic chromotographic concepts, seperation techniques basics of HPLC and determination of the suitable method to analyse biological methods.